Melanoma Mimic

Melanoma mimic: a case of multiple pagetoid Spitz nevi.

BACKGROUND Differentiating Spitz nevi from melanoma can be difficult. Pagetoid spread of melanocytes is among the features making diagnosis difficult. Rare reports of isolated pagetoid Spitz nevi exist. OBSERVATIONS We present a unique case of multiple pagetoid Spitz nevi initially diagnosed as multiple in situ melanomas. Germline karyotyping, CDK4 and CDKN2A sequencing, and comparative genom...

Nodular Melanoma

amyotrophic lateral sclerosis mimic ‎syndromes

amyotrophic lateral sclerosis (als) misdiagnosis has many broad implications for the patient and the neurologist. potentially curative treatments exist for certain als mimic syndromes, but delay in starting these therapies may have an unfavorable effect on outcome. hence, it is important to exclude similar conditions. in this review, we discuss some of the important mimics of als.

A simple mimic.

ing at the University of Arizona. Saadatmanesh developed the material, called CarbonWrap, about six years ago and now sells it through CarbonWrap Solutions. The polymer is made of woven filaments of glass, carbon and Kevlar, which are placed in a resin matrix. Its tensile strength—the force required to pull it apart—is about 200 tons per square inch, 10 times stronger than steel. The fiber cost...

A photoresponsive glycosidase mimic.

Azobenzene-3,3'-dicarboxylic acid exists in photoisomerizable (E) and (Z)-forms. Deprotonation of the carboxylic acid groups from the (E)-form occurs simultaneously, whereas in the (Z)-form it occurs in a stepwise fashion. The mono anionic form of the (Z)-isomer acts as a glycosidase mimic that proceeds through a general acid-general base catalytic mechanism. This is the first example of a phot...